Thus, DPD sufferers typically complain of emotional numbness, i.e. emotion processing, thinking and body experiencing. This detachment affects all aspects of experience, e.g. DPD patients become detached observers of themselves and their surroundings. From a psychodynamic perspective, DPD constitutes a mental escape from experiencing anything fully by suppressing emotional experiencing. Depersonalization (DP) is considered as a hard-wired stress response in reaction to extreme anxiety comprising increased alertness and suppression of emotions by prefrontal inhibition. The prevalence of DPD is around 1% in the general population, DPD has a high comorbidity with depression and anxiety disorders, and its course is typically chronic. Finally, these symptoms are a source of significant burden or impairment (DSM-V). drugs, seizures) or better explained by another mental disorder (e.g. During these experiences reality testing remains intact, and these symptoms are not caused by direct physiological effects (e.g. experiences of unreality or detachment with respect to surroundings. experiences of unreality, detachment, or being an outside observer with respect to one’s thoughts, sensations, actions or feelings and is often accompanied by derealization, i.e. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist.ĭepersonalization disorder (DPD) is characterized by persistent or recurrent depersonalization, i.e. There was no additional external funding received for this study. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: This study was in part supported by a grant from the Interdisciplinary Research Center for Neurosciences for the Center for Neuroscience at Mainz University ( ).
Received: ApAccepted: JPublished: September 13, 2013Ĭopyright: © 2013 Michal et al. PLoS ONE 8(9):Įditor: Allan Siegel, University of Medicine & Dentistry of NJ - New Jersey Medical School, United States of America (2013) Depersonalization Disorder: Disconnection of Cognitive Evaluation from Autonomic Responses to Emotional Stimuli. Citation: Michal M, Koechel A, Canterino M, Adler J, Reiner I, Vossel G, et al.
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